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    抑胃肽（GIP），人

    更新时间：2016-06-03      点击次数：1791

    Gastric Inhibitory Peptide (GIP),human

    Sequence
    (one-letter code)

    		YAEGTFISDYSIAMDKIHDFVNWLLAQKGKKNDWKHNITQ

    Sequence
    (three-letter code)

    Description

    		GIP, also known as gastric inhibitory polypeptide, or glucose-dependent insulinotropic polypeptide, is a 42-amino-acid peptide hormone synthesized in and secreted from K cells in the intestinal epithelium. There are two major GIP molecular forms in circulation, GIP (1-42) and GIP(3-42). Previous studies have demonstrated that GIP (3-42) is a degraded form of GIP (1-42) by the enzyme DPPIV. GIP secretion is primarily regulated by nutrients, especially fat. GIP exhibits potent incretin activity in rodent and human subjects. The primary action of GIP is the stimulation of glucose-dependent insulin secretion. GIP may also play a role in adipocyte biology.

    Solubility

    		The peptide is soluble in water. The contents of this vial have been accuray determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents.

    MW

    		4983.600

    Formula

    		C226H338N60O66S1

    Purity

    		> 95%

    Storage

    		Store the peptide at -20°C.

     

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